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TLR4 is one such PRR that detects damage-associated molecular patterns (DAMPs) created by stressed and dying cells and pathogen-associated molecular patterns (PAMPs) like bacterial lipopolysaccharide (LPS) (Guo et al., 2022

This dysfunction may occur in isolated cells or affect multiple systems , depending on severity and cause

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Cigarette tar mediates macrophage ferroptosis in atherosclerosis through the hepcidin/FPN/SLC7A11 signaling pathway

Epidemiological studies indicate clear links between heavy metal exposure and CVD-related risks and outcomes